{"id":1563,"date":"2024-09-21T10:14:00","date_gmt":"2024-09-21T08:14:00","guid":{"rendered":"https:\/\/nanosmartlab.cnr.it\/?p=1563"},"modified":"2025-05-26T10:20:51","modified_gmt":"2025-05-26T08:20:51","slug":"sensostec-project-resultsthe-european-nights-of-researchers-in-naples","status":"publish","type":"post","link":"https:\/\/nanosmartlab.cnr.it\/?p=1563","title":{"rendered":"SENSOSTEC Project Results@The European Nights of Researchers in Naples"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The <strong>PRIN project \u201cSENSOSTEC\u201d<\/strong> \u2014 <em>Development of a Plasmonic Nanobiosensor for the Rapid Diagnosis of Shiga Toxin-Producing E. coli Infections at the Point of Care<\/em> \u2014 is a groundbreaking initiative coordinated by <strong>Dr. Lucia Petti<\/strong> (ISASI-CNR), in close collaboration with <strong>Prof. Brigotti<\/strong> from the Department of Specialized, Diagnostic and Experimental Medicine at the <strong>University of Bologna<\/strong>, and <strong>Dr. Stefano Morabito<\/strong>, Director of the <strong>European Reference Laboratory for <em>E. coli<\/em><\/strong> at <strong>ISS<\/strong>, along with their dedicated research teams.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The project is funded through <strong>NextGenerationEU<\/strong> (CUP B53C22003100002) and aims to revolutionize the detection of <strong>Shiga toxin (Stx)<\/strong> \u2014 a potent biological agent produced by <em>Escherichia coli<\/em> strains, responsible for severe gastrointestinal infections and complications such as <strong>hemolytic uremic syndrome<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This afternoon, some of the project\u2019s exciting advancements will be presented by <strong>Dr. Alessia Milano<\/strong> and <strong>Dr. Bryan Guilcapi<\/strong> at the <strong>European Researchers&#8217; Night<\/strong> in <strong>Piazza Dante, Naples<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the core of SENSOSTEC lies the development of a novel <strong>biophotonic and bioplasmonic platform<\/strong> capable of delivering <strong>rapid, reliable, and highly sensitive<\/strong> qualitative and quantitative detection of Shiga toxin in complex biological matrices.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Two complementary nanofabrication strategies are being used to create next-generation recognition systems:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Top-down<\/strong> approaches, utilizing <strong>electron beam lithography<\/strong> to engineer advanced plasmonic <strong>metasurfaces<\/strong>.<\/li>\n\n\n\n<li><strong>Bottom-up<\/strong> synthesis of <strong>self-assembled gold nanoparticle monolayers<\/strong>, forming responsive and selective nanostructures.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">These nanostructured biosensors demonstrate a powerful capability to detect Shiga toxin with <strong>high specificity and speed<\/strong>, paving the way for future <strong>point-of-care diagnostic technologies<\/strong>.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"has-text-align-right wp-block-paragraph\"><em>This multidisciplinary effort highlights how advanced nanotechnology and photonics can be translated into impactful tools for public health. -B.G.-<\/em><\/p>\n<\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The PRIN project \u201cSENSOSTEC\u201d \u2014 Development of a Plasmonic Nanobiosensor for the Rapid [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1564,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[11],"tags":[10],"class_list":["post-1563","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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