We are pleased to announce the publication of our new article in Biosensors and Bioelectronics: X, titled:
“Flexible gold nanoparticle SERS tape for rapid, label-free and ultrasensitive detection and differentiation of Shiga toxin variants”.
This study presents the development of flexible SERS (Surface-Enhanced Raman Scattering) substrates obtained by transferring self-assembled plasmonic nanostructures onto polymeric supports, enabling mechanically compliant and wearable sensors for biochemical detection.
The work demonstrates the capability of these plasmonic platforms to achieve label-free SERS identification and discrimination of three Shiga toxins produced by Escherichia coli directly in human serum, without the need for chemical labels or complex sample preparation.
Advanced multivariate analysis based on Principal Component Analysis (PCA) was employed to successfully classify and distinguish the spectral fingerprints of the different toxins, highlighting the strong potential of SERS combined with data-driven analytics for rapid and reliable biosensing applications.
This research represents an important step toward the realization of portable diagnostic systems for real-time pathogen and toxin detection in complex biological environments.
📄 Read the full paper:
https://doi.org/10.1016/j.biosx.2025.100696
Congratulations to all the authors for this significant achievement!
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